Properties
storage conditions: Store at +15°C to +25°C.
biological source: synthetic
Form: powder or crystals
Packaging:
pkg of 1 kg
pkg of 5 kg
pkg of 10 kg
Solubility: water: soluble (Up to 1.3M (room temp))
Suitability: suitable for manufacturing use (cell culture media)
Storage temp.: room temp
Description
General description
Modified amino acids are inhouse manufactured amino acid derivatives with specific properties enabling the intensification of cell culture processes.
Together with the companion product Phospho-L-Tyrosine disodium Salt disodium salt, the new modified amino acid S-Sulfocysteine sodium salt can be used as replacement for cysteine to generate highly concentrated, neutral pH feeds. Both modified amino acids eliminate the need for alkaline feeds, which are normally applied to ensure solubility and stability of the unmodified amino acids tyrosine and cysteine.
Features and Benefits
Reduced complexity in fed-batch process
High concentrations of modified cysteine in main feeds at neutral pH
Prevention of caustic shocks in the bioreactor due to high pH feeds
More convenient preparation process with less contamination risks
Reduction of recombinant protein fragmentation and decrease in trisulfide bond content
Higher feed stability at room temperature