Phospho-L-Tyrosine Disodium Salt
Phospho-L-Tyrosine Disodium Salt
storage conditions: Store at +2°C to +8°C.
biological source: synthetic
Form: powder or crystals
Packaging:
pkg of 1 kg (in PE drum, 2 inner PE liners )
pkg of 10 kg (in PE drum, 2 inner PE liners)
pH: 5.5-9.0 (10 g/L in H2O)
Solubility: 25 g/L
≤70 g/L (in complex feed)
Suitability: suitable for manufacturing use (cell culture)
General description
Modified amino acids are inhouse manufactured amino acid derivatives with specific properties enabling the intensification of cell culture processes.
Together with the companion product Sulfo-Cysteine sodium salt, the new modified amino acid Phospho-Tyrosine disodium salt can be used as replacement for tyrosine to generate highly concentrated, neutral pH feeds. Both modified amino acids eliminate the need for alkaline feeds, which are normally applied to ensure solubility and stability of the unmodified amino acids tyrosine and cysteine.
Features and Benefits
Reduced complexity in fed-batch process
High concentrations of modified tyrosine in main feeds at neutral pH
Enhanced solubility up to 70g/l in complex feed
Prevention of caustic shocks in the bioreactor due to high pH feeds
More convenient preparation process with less contamination risks
Higher feed stability at room temperature
